OpenEvidence CI Integration

Overview

Set up CI/CD for OpenEvidence clinical decision support integrations: run unit tests with mocked evidence query and citation responses on every PR, validate live API connectivity for clinical queries on merge to main. OpenEvidence provides AI-powered medical evidence retrieval and clinical decision support, so CI pipelines verify query formatting, evidence parsing, citation extraction, and response quality scoring.

GitHub Actions Workflow

# .github/workflows/openevidence-ci.yml
name: OpenEvidence CI
on:
  pull_request:
    paths: ['src/openevidence/**', 'tests/**']
  push:
    branches: [main]

jobs:
  unit-tests:
    runs-on: ubuntu-latest
    steps:
      - uses: actions/checkout@v4
      - uses: actions/setup-node@v4
        with: { node-version: '20' }
      - run: npm ci
      - run: npm test -- --reporter=verbose

  integration-tests:
    if: github.ref == 'refs/heads/main'
    needs: unit-tests
    runs-on: ubuntu-latest
    steps:
      - uses: actions/checkout@v4
      - uses: actions/setup-node@v4
        with: { node-version: '20' }
      - run: npm ci
      - run: npm run test:integration
        env:
          OPENEVIDENCE_API_KEY: ${{ secrets.OPENEVIDENCE_API_KEY }}

Mock-Based Unit Tests

// tests/openevidence-service.test.ts
import { describe, it, expect, vi } from 'vitest';
import { queryEvidence, extractCitations } from '../src/openevidence-service';

vi.mock('../src/openevidence-client', () => ({
  OpenEvidenceClient: vi.fn().mockImplementation(() => ({
    query: vi.fn().mockResolvedValue({
      answer: 'Current evidence supports early intervention with GLP-1 agonists...',
      confidence: 0.92,
      citations: [
        { title: 'NEJM 2025 Meta-Analysis', doi: '10.1056/NEJMoa2501234', year: 2025 },
        { title: 'Lancet Diabetes Review', doi: '10.1016/S2213-8587(25)00123', year: 2025 },
      ],
      evidenceLevel: 'high',
    }),
    listQueries: vi.fn().mockResolvedValue({
      queries: [{ id: 'q_abc', question: 'GLP-1 efficacy', status: 'completed' }],
    }),
  })),
}));

describe('OpenEvidence Service', () => {
  it('queries clinical evidence with citations', async () => {
    const result = await queryEvidence('GLP-1 agonist efficacy for type 2 diabetes');
    expect(result.confidence).toBeGreaterThan(0.9);
    expect(result.citations).toHaveLength(2);
  });

  it('extracts citation DOIs from response', async () => {
    const citations = await extractCitations('q_abc');
    expect(citations[0].doi).toMatch(/^10\.\d+/);
  });
});

Integration Tests

// tests/integration/openevidence.integration.test.ts
import { describe, it, expect } from 'vitest';

const hasKey = !!process.env.OPENEVIDENCE_API_KEY;

describe.skipIf(!hasKey)('OpenEvidence Live API', () => {
  it('queries clinical evidence', async () => {
    const res = await fetch('https://api.openevidence.com/v1/query', {
      method: 'POST',
      headers: {
        'Authorization': `Bearer ${process.env.OPENEVIDENCE_API_KEY}`,
        'Content-Type': 'application/json',
      },
      body: JSON.stringify({ question: 'Aspirin dosing for secondary prevention' }),
    });
    expect(res.status).toBe(200);
    const body = await res.json();
    expect(body).toHaveProperty('answer');
    expect(body).toHaveProperty('citations');
  });
});

Error Handling

CI Issue	Cause	Fix
401 Unauthorized	Invalid API key	Regenerate at openevidence.com account settings
Empty citations array	Query too vague for evidence matching	Use specific clinical terms with condition and intervention
Low confidence score	Insufficient published evidence	Check evidence level field and handle low confidence gracefully
Rate limit (429)	Too many queries in test suite	Add throttling between clinical queries (1 req/sec)
Response timeout	Complex query requiring deep search	Increase fetch timeout to 30s for clinical evidence lookups

Resources

• OpenEvidence Platform
• OpenEvidence API Documentation
• GitHub Actions Secrets

Next Steps

See openevidence-deploy-integration.